What is PGT (Preimplantation Genetic Testing)?

PGT is a technique that examines the genetic makeup of embryos created through in-vitro fertilization (IVF). The procedure is done by extracting one or more cells from an embryo at the blastocyst stage (when the embryo has around 100-150 cells) and analyzing the cells for genetic conditions or chromosomal abnormalities. This information can then be used to select the most viable embryos for transfer to the uterus, increasing the chances of a successful pregnancy.
There are different types of PGT:
– PGT-A (Preimplantation Genetic Testing for Aneuploidies) is used to test for chromosomal abnormalities, such as Down Syndrome, Turner Syndrome, and Edwards Syndrome.
– PGT-M (Preimplantation Genetic Testing for Monogenic/Single Gene Defects) is used to test for genetic disorders caused by mutations in specific genes, such as cystic fibrosis, Tay-Sachs, and Sickle Cell Anemia.
– PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements) is used to test for structural chromosomal abnormalities, such as translocations or inversions.
The procedure is performed during the in-vitro fertilization (IVF) process. Once the eggs are fertilized with sperm, they are grown in the laboratory for several days to form embryos. Then, a small number of cells are removed from the embryos and analyzed for genetic disorders or chromosomal abnormalities. The embryos that are found to be free of the genetic or chromosomal condition are then selected for transfer to the uterus.
For more information, consult Chembur Fertility Clinic the Best IVF Clinic in Mumbai.